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The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Directly Enhances the Contractile Recovery of Mouse Hearts at a Concentration Equivalent to that Achieved with Standard Dosing in Humans

Despite a similar mechanism of action underlying their glucose-lowering effects in type 2 diabetes, dipeptidyl peptidase-4 (DPP-4) inhibitors have diverse molecular structures, raising the prospect of agent-specific, glucose-independent actions. To explore the issue of possible DPP-4 inhibitor cardi...

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Detalles Bibliográficos
Autores principales: Batchu, Sri Nagarjun, Yerra, Veera Ganesh, Liu, Youan, Advani, Suzanne L., Klein, Thomas, Advani, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460951/
https://www.ncbi.nlm.nih.gov/pubmed/32796688
http://dx.doi.org/10.3390/ijms21165756