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Premature Activation of Immune Transcription Programs in Autoimmune-Predisposed Mouse Embryonic Stem Cells and Blastocysts

Autoimmune diabetes is a complex multifactorial disease with genetic and environmental factors playing pivotal roles. While many genes associated with the risk of diabetes have been identified to date, the mechanisms by which external triggers contribute to the genetic predisposition remain unclear....

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Detalles Bibliográficos
Autores principales: Kirak, Oktay, Ke, Eugene, Yang, Kevin Y., Schwarz, Anna, Plate, Lars, Nham, Amy, Abadejos, Justin R., Valencia, Anna, Wiseman, R. Luke, Lui, Kathy O., Ku, Manching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460978/
https://www.ncbi.nlm.nih.gov/pubmed/32796510
http://dx.doi.org/10.3390/ijms21165743