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Complex III Inhibition-Induced Pulmonary Hypertension Affects the Mitochondrial Proteomic Landscape

The mitochondria play a vital role in controlling cell metabolism and regulating crucial cellular outcomes. We previously demonstrated that chronic inhibition of the mitochondrial complex III in rats by Antimycin A (AA) induced sustained pulmonary vasoconstriction. On the metabolic level, AA-induced...

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Detalles Bibliográficos
Autores principales: James, Joel, Valuparampil Varghese, Mathews, Vasilyev, Mikhail, Langlais, Paul R., Tofovic, Stevan P., Rafikova, Olga, Rafikov, Ruslan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461049/
https://www.ncbi.nlm.nih.gov/pubmed/32784406
http://dx.doi.org/10.3390/ijms21165683