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Towards the Development of AgoKirs: New Pharmacological Activators to Study K(ir)2.x Channel and Target Cardiac Disease

Inward rectifier potassium ion channels (I(K1)-channels) of the K(ir)2.x family are responsible for maintaining a stable negative resting membrane potential in excitable cells, but also play a role in processes of non-excitable tissues, such as bone development. I(K1)-channel loss-of-function, eithe...

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Detalles Bibliográficos
Autores principales: van der Schoor, Laura, van Hattum, Emma J., de Wilde, Sophie M., Harlianto, Netanja I., van Weert, Aart-Jan, Bloothooft, Meye, van der Heyden, Marcel A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461056/
https://www.ncbi.nlm.nih.gov/pubmed/32796537
http://dx.doi.org/10.3390/ijms21165746