Connexin Mutants Compromise the Lens Circulation and Cause Cataracts through Biomineralization

Gap junction-mediated intercellular communication facilitates the circulation of ions, small molecules, and metabolites in the avascular eye lens. Mutants of the lens fiber cell gap junction proteins, connexin46 (Cx46) and connexin50 (Cx50), cause cataracts in people and in mice. Studies in mouse mo...

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Detalles Bibliográficos
Autores principales: Berthoud, Viviana M., Gao, Junyuan, Minogue, Peter J., Jara, Oscar, Mathias, Richard T., Beyer, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461132/
https://www.ncbi.nlm.nih.gov/pubmed/32823750
http://dx.doi.org/10.3390/ijms21165822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461132/
https://www.ncbi.nlm.nih.gov/pubmed/32823750
http://dx.doi.org/10.3390/ijms21165822

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