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NONO promotes hepatocellular carcinoma progression by enhancing fatty acids biosynthesis through interacting with ACLY mRNA

BACKGROUND: Dysregulation of fatty acid (FA) metabolism is involved in hepatocellular carcinoma (HCC) development. Non-POU domain-containing octamer binding protein (NONO), known as the component of nuclear paraspeckles, has recently been found to promote HCC progression. In this study, we investiga...

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Detalles Bibliográficos
Autores principales: Ding, Hongda, Liu, Junpeng, Wang, Caibin, Su, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461318/
https://www.ncbi.nlm.nih.gov/pubmed/32884448
http://dx.doi.org/10.1186/s12935-020-01520-4