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Histone H4 directly stimulates neutrophil activation through membrane permeabilization

Extracellular histones have been implicated as a cause of tissue inflammatory injury in a variety of disorders including sepsis, lung, and liver diseases. However, little is known about their interactions with neutrophils and how this might contribute to injury. Here, it is shown that histone H4 act...

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Detalles Bibliográficos
Autores principales: Hsieh, I‐Ni, Deluna, Xavier, White, Mitchell R., Hartshorn, Kevan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461478/
https://www.ncbi.nlm.nih.gov/pubmed/32803840
http://dx.doi.org/10.1002/JLB.3A0620-342R