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Deep Learning Modeling of Androgen Receptor Responses to Prostate Cancer Therapies
Gain-of-function mutations in human androgen receptor (AR) are among the major causes of drug resistance in prostate cancer (PCa). Identifying mutations that cause resistant phenotype is of critical importance for guiding treatment protocols, as well as for designing drugs that do not elicit adverse...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461580/ https://www.ncbi.nlm.nih.gov/pubmed/32823970 http://dx.doi.org/10.3390/ijms21165847 |