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Deep Learning Modeling of Androgen Receptor Responses to Prostate Cancer Therapies

Gain-of-function mutations in human androgen receptor (AR) are among the major causes of drug resistance in prostate cancer (PCa). Identifying mutations that cause resistant phenotype is of critical importance for guiding treatment protocols, as well as for designing drugs that do not elicit adverse...

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Detalles Bibliográficos
Autores principales: Snow, Oliver, Lallous, Nada, Ester, Martin, Cherkasov, Artem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461580/
https://www.ncbi.nlm.nih.gov/pubmed/32823970
http://dx.doi.org/10.3390/ijms21165847