N-(2′-Hydroxyphenyl)-2-Propylpentanamide (HO-AAVPA) Inhibits HDAC1 and Increases the Translocation of HMGB1 Levels in Human Cervical Cancer Cells

N-(2′-hydroxyphenyl)-2-propylpentanamide (HO-AAVPA) is a VPA derivative designed to be a histone deacetylase (HDAC) inhibitor. HO-AAVPA has better antiproliferative effect than VPA in cancer cell lines. Therefore, in this work, the inhibitory effect of HO-AAVPA on HDAC1, HDAC6, and HDAC8 was determi...

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Detalles Bibliográficos
Autores principales: Sixto-López, Yudibeth, Rosales-Hernández, Martha Cecilia, Contis-Montes de Oca, Arturo, Fragoso-Morales, Leticia Guadalupe, Mendieta-Wejebe, Jessica Elena, Correa-Basurto, Ana María, Abarca-Rojano, Edgar, Correa-Basurto, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461584/
https://www.ncbi.nlm.nih.gov/pubmed/32824279
http://dx.doi.org/10.3390/ijms21165873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461584/
https://www.ncbi.nlm.nih.gov/pubmed/32824279
http://dx.doi.org/10.3390/ijms21165873

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