Directed Blocking of TGF-β Receptor I Binding Site Using Tailored Peptide Segments to Inhibit its Signaling Pathway

BACKGROUND: TGF-β isoforms play crucial roles in diverse cellular processes. Therefore, targeting and inhibiting TGF-β signaling pathway provides a potential therapeutic opportunity. TGF-β isoforms bind and bring the receptors (TβRII and TβRI) together to form a signaling complex in an ordered manne...

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Detalles Bibliográficos
Autores principales: Sepehri, Sepideh, Arab, S. Shahriar, Behmanesh, Mehrdad, H. Sajedi, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Genetic Engineering and Biotechnology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461711/
https://www.ncbi.nlm.nih.gov/pubmed/32884960
http://dx.doi.org/10.30498/IJB.2020.197161.2561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461711/
https://www.ncbi.nlm.nih.gov/pubmed/32884960
http://dx.doi.org/10.30498/IJB.2020.197161.2561

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