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CrisPam: SNP-Derived PAM Analysis Tool for Allele-Specific Targeting of Genetic Variants Using CRISPR-Cas Systems

Clustered regularly interspaced short palindromic repeats (CRISPR) is a promising novel technology that holds the potential of treating genetic diseases. Safety and specificity of the treatment are to be further studied and developed prior to implementation of the technology into the clinic. The gui...

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Detalles Bibliográficos
Autores principales: Rabinowitz, Roy, Almog, Shiri, Darnell, Roy, Offen, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461778/
https://www.ncbi.nlm.nih.gov/pubmed/33014011
http://dx.doi.org/10.3389/fgene.2020.00851