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DNA Methylation Manipulation of Memory Genes Is Involved in Sevoflurane Induced Cognitive Impairments in Aged Rats

DNA methylation is an essential epigenetic mechanism involving in gene transcription modulation. An age-related increase in promoter methylation has been observed for neuronal activity and memory genes, and participates in neurological disorders. However, the position and precise mechanism of DNA me...

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Detalles Bibliográficos
Autores principales: Ni, Cheng, Qian, Min, Geng, Jiao, Qu, Yinyin, Tian, Yi, Yang, Ning, Li, Shuai, Zheng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461785/
https://www.ncbi.nlm.nih.gov/pubmed/33013350
http://dx.doi.org/10.3389/fnagi.2020.00211