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Understanding the Role of Mucosal-Associated Invariant T-Cells in Non-human Primate Models of HIV Infection

Chronic HIV infection causes systemic immune activation and dysregulation, resulting in the impairment of most T-cell subsets including MAIT cells. Multiple human cohort studies demonstrate MAIT cells are selectively depleted in the peripheral blood and lymphoid tissues during HIV infection, with in...

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Detalles Bibliográficos
Autores principales: Barber-Axthelm, Isaac M., Kent, Stephen J., Juno, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461791/
https://www.ncbi.nlm.nih.gov/pubmed/33013862
http://dx.doi.org/10.3389/fimmu.2020.02038