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Differential Host Pro-Inflammatory Response to Mycobacterial Cell Wall Lipids Regulated by the Mce1 Operon

The cell wall of wild-type (WT) Mycobacterium tuberculosis (Mtb), an etiologic agent of tuberculosis (TB) and a Mtb strain disrupted in a 13-gene operon mce1 (Δmce1) varies by more than 400 lipid species. Here, we examined Mtb lipid-induced response in murine macrophage, as well as in human T-cell s...

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Detalles Bibliográficos
Autores principales: Petrilli, Jéssica D., Müller, Igor, Araújo, Luana E., Cardoso, Thiago M., Carvalho, Lucas P., Barros, Bruna C., Teixeira, Maurício, Arruda, Sérgio, Riley, Lee W., Queiroz, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461851/
https://www.ncbi.nlm.nih.gov/pubmed/32973761
http://dx.doi.org/10.3389/fimmu.2020.01848