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Critical Role of AdipoR1 in Regulating Th17 Cell Differentiation Through Modulation of HIF-1α-Dependent Glycolysis

We previously reported that adiponectin (AD) promotes naïve T cell differentiation into Th17 cells and participates in synovial inflammation and the bone erosion process in patients with rheumatoid arthritis. Here, we use a T cell lineage adiponectin receptor 1 (AdipoR1) conditional knockout model t...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Wang, Lei, Jiang, Jintao, Lin, Shiyu, Luo, Aishu, Zhao, Pengfei, Tan, Wenfeng, Zhang, Miaojia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461876/
https://www.ncbi.nlm.nih.gov/pubmed/32973810
http://dx.doi.org/10.3389/fimmu.2020.02040