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Reducing Glutamate Uptake in Rat Hippocampal Slices Enhances Astrocytic Membrane Depolarization While Down-Regulating CA3–CA1 Synaptic Response

The majority of synaptic activity in the brain consists of glutamatergic transmission, and there are numerous mechanisms, both intra- and inter-cellular that regulate this excitatory synaptic activity. Importantly, uptake of glutamate plays an important role and a reduced level of astrocytic glutama...

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Detalles Bibliográficos
Autores principales: Srivastava, Ipsit, Vazquez-Juarez, Erika, Lindskog, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461906/
https://www.ncbi.nlm.nih.gov/pubmed/32973483
http://dx.doi.org/10.3389/fnsyn.2020.00037