Key Players in the Mutant p53 Team: Small Molecules, Gene Editing, Immunotherapy

The transcription factor p53 is a key tumor suppressor that is inactivated in almost all cancers due to either point mutations in the TP53 gene or overexpression of its negative regulators. The p53 protein is known as the “cellular gatekeeper” for its roles in facilitating DNA repair, cell cycle arr...

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Detalles Bibliográficos
Autores principales: Chasov, Vitaly, Mirgayazova, Regina, Zmievskaya, Ekaterina, Khadiullina, Raniya, Valiullina, Aygul, Stephenson Clarke, Joseph, Rizvanov, Albert, Baud, Matthias G. J., Bulatov, Emil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461930/
https://www.ncbi.nlm.nih.gov/pubmed/32974171
http://dx.doi.org/10.3389/fonc.2020.01460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461930/
https://www.ncbi.nlm.nih.gov/pubmed/32974171
http://dx.doi.org/10.3389/fonc.2020.01460

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