Arming Anti-EGFRvIII CAR-T With TGFβ Trap Improves Antitumor Efficacy in Glioma Mouse Models

Glioblastoma (GBM) is an aggressive malignancy with poor prognosis. New therapeutic strategies for GBM are urgently needed. Although clinical studies have demonstrated the feasibility and safety of chimeric antigen receptor (CAR) T cell therapy for GBM, its efficacy has not been that impressive. The...

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Detalles Bibliográficos
Autores principales: Li, You, Wu, Huifang, Chen, Gang, Wei, Xiaofan, Wang, Chunyu, Zhou, Shanshan, Huang, Ailing, Zhang, Zui, Zhan, Changyou, Wu, Yanling, Ying, Tianlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461942/
https://www.ncbi.nlm.nih.gov/pubmed/32974124
http://dx.doi.org/10.3389/fonc.2020.01117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461942/
https://www.ncbi.nlm.nih.gov/pubmed/32974124
http://dx.doi.org/10.3389/fonc.2020.01117

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