Tn Antigen Expression Contributes to an Immune Suppressive Microenvironment and Drives Tumor Growth in Colorectal Cancer

Expression of the tumor-associated glycan Tn antigen (αGalNAc-Ser/Thr) has been correlated to poor prognosis and metastasis in multiple cancer types. However, the exact mechanisms exerted by Tn antigen to support tumor growth are still lacking. One emerging hallmark of cancer is evasion of immune de...

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Detalles Bibliográficos
Autores principales: Cornelissen, Lenneke A. M., Blanas, Athanasios, Zaal, Anouk, van der Horst, Joost C., Kruijssen, Laura J. W., O’Toole, Tom, van Kooyk, Yvette, van Vliet, Sandra J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461972/
https://www.ncbi.nlm.nih.gov/pubmed/33014816
http://dx.doi.org/10.3389/fonc.2020.01622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461972/
https://www.ncbi.nlm.nih.gov/pubmed/33014816
http://dx.doi.org/10.3389/fonc.2020.01622

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