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Tn Antigen Expression Contributes to an Immune Suppressive Microenvironment and Drives Tumor Growth in Colorectal Cancer
Expression of the tumor-associated glycan Tn antigen (αGalNAc-Ser/Thr) has been correlated to poor prognosis and metastasis in multiple cancer types. However, the exact mechanisms exerted by Tn antigen to support tumor growth are still lacking. One emerging hallmark of cancer is evasion of immune de...
Autores principales: | Cornelissen, Lenneke A. M., Blanas, Athanasios, Zaal, Anouk, van der Horst, Joost C., Kruijssen, Laura J. W., O’Toole, Tom, van Kooyk, Yvette, van Vliet, Sandra J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461972/ https://www.ncbi.nlm.nih.gov/pubmed/33014816 http://dx.doi.org/10.3389/fonc.2020.01622 |
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