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Thymic Engraftment by in vitro-Derived Progenitor T Cells in Young and Aged Mice

T cells play a critical role in mediating antigen-specific and long-term immunity against viral and bacterial pathogens, and their development relies on the highly specialized thymic microenvironment. T cell immunodeficiency can be acquired in the form of inborn errors, or can result from perturbati...

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Detalles Bibliográficos
Autores principales: Singh, Jastaranpreet, Mohtashami, Mahmood, Anderson, Graham, Zúñiga-Pflücker, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462002/
https://www.ncbi.nlm.nih.gov/pubmed/32973763
http://dx.doi.org/10.3389/fimmu.2020.01850