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Thymic Engraftment by in vitro-Derived Progenitor T Cells in Young and Aged Mice
T cells play a critical role in mediating antigen-specific and long-term immunity against viral and bacterial pathogens, and their development relies on the highly specialized thymic microenvironment. T cell immunodeficiency can be acquired in the form of inborn errors, or can result from perturbati...
Autores principales: | Singh, Jastaranpreet, Mohtashami, Mahmood, Anderson, Graham, Zúñiga-Pflücker, Juan Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462002/ https://www.ncbi.nlm.nih.gov/pubmed/32973763 http://dx.doi.org/10.3389/fimmu.2020.01850 |
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