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The Daam2–VHL–Nedd4 axis governs developmental and regenerative oligodendrocyte differentiation

Dysregulation of the ubiquitin–proteasomal system (UPS) enables pathogenic accumulation of disease-driving proteins in neurons across a host of neurological disorders. However, whether and how the UPS contributes to oligodendrocyte dysfunction and repair after white matter injury (WMI) remains undef...

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Detalles Bibliográficos
Autores principales: Ding, Xiaoyun, Jo, Juyeon, Wang, Chih-Yen, Cristobal, Carlo D., Zuo, Zhongyuan, Ye, Qi, Wirianto, Marvin, Lindeke-Myers, Aaron, Choi, Jong Min, Mohila, Carrie A., Kawabe, Hiroshi, Jung, Sung Yun, Bellen, Hugo J., Yoo, Seung-Hee, Lee, Hyun Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462057/
https://www.ncbi.nlm.nih.gov/pubmed/32792353
http://dx.doi.org/10.1101/gad.338046.120