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The nuclear cap-binding complex as choreographer of gene transcription and pre-mRNA processing

The largely nuclear cap-binding complex (CBC) binds to the 5′ caps of RNA polymerase II (RNAPII)-synthesized transcripts and serves as a dynamic interaction platform for a myriad of RNA processing factors that regulate gene expression. While influence of the CBC can extend into the cytoplasm, here w...

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Detalles Bibliográficos
Autores principales: Rambout, Xavier, Maquat, Lynne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462061/
https://www.ncbi.nlm.nih.gov/pubmed/32873578
http://dx.doi.org/10.1101/gad.339986.120