Cargando…
The nuclear cap-binding complex as choreographer of gene transcription and pre-mRNA processing
The largely nuclear cap-binding complex (CBC) binds to the 5′ caps of RNA polymerase II (RNAPII)-synthesized transcripts and serves as a dynamic interaction platform for a myriad of RNA processing factors that regulate gene expression. While influence of the CBC can extend into the cytoplasm, here w...
Autores principales: | Rambout, Xavier, Maquat, Lynne E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462061/ https://www.ncbi.nlm.nih.gov/pubmed/32873578 http://dx.doi.org/10.1101/gad.339986.120 |
Ejemplares similares
-
Coupling pre-mRNA splicing and 3′ end formation to mRNA export: alternative ways to punch the nuclear export clock
por: Elbarbary, Reyad A., et al.
Publicado: (2016) -
3′READS + RIP defines differential Staufen1 binding to alternative 3′UTR isoforms and reveals structures and sequence motifs influencing binding and polysome association
por: Zheng, Dinghai, et al.
Publicado: (2020) -
mRNA–mRNA duplexes that auto-elicit Staufen1-mediated mRNA decay
por: Gong, Chenguang, et al.
Publicado: (2013) -
A nuclear cap-binding complex binds Balbiani ring pre-mRNA cotranscriptionally and accompanies the ribonucleoprotein particle during nuclear export
Publicado: (1996) -
Nsp14 of SARS-CoV-2 inhibits mRNA processing and nuclear export by targeting the nuclear cap-binding complex
por: Katahira, Jun, et al.
Publicado: (2023)