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UTteR control through miRs: fine-tuning ATXN1 levels to prevent ataxia
Pathomechanistic studies of neurodegenerative diseases have documented the toxic effects of mutant protein expression, misfolding, and aggregation. However, alterations in the expression of the corresponding wild-type (WT) gene, due to either variations in copy number or transcriptional regulation,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462066/ https://www.ncbi.nlm.nih.gov/pubmed/32873576 http://dx.doi.org/10.1101/gad.343020.120 |