ADAR-deficiency perturbs the global splicing landscape in mouse tissues

Adenosine-to-inosine RNA editing and pre-mRNA splicing largely occur cotranscriptionally and influence each other. Here, we use mice deficient in either one of the two editing enzymes ADAR (ADAR1) or ADARB1 (ADAR2) to determine the transcriptome-wide impact of RNA editing on splicing across differen...

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Detalles Bibliográficos
Autores principales: Kapoor, Utkarsh, Licht, Konstantin, Amman, Fabian, Jakobi, Tobias, Martin, David, Dieterich, Christoph, Jantsch, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462079/
https://www.ncbi.nlm.nih.gov/pubmed/32727871
http://dx.doi.org/10.1101/gr.256933.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462079/
https://www.ncbi.nlm.nih.gov/pubmed/32727871
http://dx.doi.org/10.1101/gr.256933.119

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