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Diploid genome architecture revealed by multi-omic data of hybrid mice

Although mammalian genomes are diploid, previous studies extensively investigated the average chromatin architectures without considering the differences between homologous chromosomes. We generated Hi-C, ChIP-seq, and RNA-seq data sets from CD4 T cells of B6, Cast, and hybrid mice, to investigate t...

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Detalles Bibliográficos
Autores principales: Han, Zhijun, Cui, Kairong, Placek, Katarzyna, Hong, Ni, Lin, Chengqi, Chen, Wei, Zhao, Keji, Jin, Wenfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462080/
https://www.ncbi.nlm.nih.gov/pubmed/32759226
http://dx.doi.org/10.1101/gr.257568.119