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A single copy of large tumor suppressor 1 or large tumor suppressor 2 is sufficient for normal hematopoiesis
BACKGROUND: Hematopoietic stem cells (HSCs) have the ability to differentiate into all subsets of blood cells and self-renew. Large tumor suppressor 1 (LATS1) and large tumor suppressor 2 (LATS2) kinases are essential for cell cycle regulation, organism fitness, genome integrity, and cancer preventi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462215/ https://www.ncbi.nlm.nih.gov/pubmed/32826458 http://dx.doi.org/10.1097/CM9.0000000000000934 |