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Tumor vascular status controls oxygen delivery facilitated by infused polymerized hemoglobins with varying oxygen affinity
Oxygen (O(2)) delivery facilitated by hemoglobin (Hb)-based O(2) carriers (HBOCs) is a promising strategy to increase the effectiveness of chemotherapeutics for treatment of solid tumors. However, the heterogeneous vascular structures present within tumors complicates evaluating the oxygenation pote...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462268/ https://www.ncbi.nlm.nih.gov/pubmed/32817659 http://dx.doi.org/10.1371/journal.pcbi.1008157 |