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Metabolism-based isolation of invasive glioblastoma cells with specific gene signatures and tumorigenic potential

BACKGROUND: Glioblastoma (GBM) is a highly aggressive brain tumor with rapid subclonal diversification, harboring molecular abnormalities that vary temporospatially, a contributor to therapy resistance. Fluorescence-guided neurosurgical resection utilizes the administration of 5-aminolevulinic acid...

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Detalles Bibliográficos
Autores principales: Smith, Stuart James, Rowlinson, Jonathan, Estevez-Cebrero, Maria, Onion, David, Ritchie, Alison, Clarke, Phil, Wood, Katie, Diksin, Mohammed, Lourdusamy, Anbarasu, Grundy, Richard Guy, Rahman, Ruman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462276/
https://www.ncbi.nlm.nih.gov/pubmed/32904996
http://dx.doi.org/10.1093/noajnl/vdaa087