Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state

Anthrax toxin is the major virulence factor secreted by Bacillus anthracis, causing high mortality in humans and other mammals. It consists of a membrane translocase, known as protective antigen (PA), that catalyzes the unfolding of its cytotoxic substrates lethal factor (LF) and edema factor (EF),...

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Detalles Bibliográficos
Autores principales: Antoni, Claudia, Quentin, Dennis, Lang, Alexander E., Aktories, Klaus, Gatsogiannis, Christos, Raunser, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462287/
https://www.ncbi.nlm.nih.gov/pubmed/32810181
http://dx.doi.org/10.1371/journal.ppat.1008530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462287/
https://www.ncbi.nlm.nih.gov/pubmed/32810181
http://dx.doi.org/10.1371/journal.ppat.1008530

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