3-Hydroxypyrimidine-2, 4-dione Derivatives as HIV Reverse Transcriptase-Associated RNase H Inhibitors: QSAR Analysis and Molecular Docking Studies

AIDS, as a lethal disease, is caused by infection with the HIV virus that affects millions of people. Three essential enzymes should be encoded for replication of HIV virus: protease, integrase and reverse transcriptase (RT). RT has two different activities including DNA polymerase and ribonuclease...

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Detalles Bibliográficos
Autores principales: Mostoufi, Azar, Chamkouri, Narges, Kordrostami, Samaneh, Alghasibabaahmadi, Elham, Mojaddami, Ayyub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462486/
https://www.ncbi.nlm.nih.gov/pubmed/32922472
http://dx.doi.org/10.22037/ijpr.2020.1101004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462486/
https://www.ncbi.nlm.nih.gov/pubmed/32922472
http://dx.doi.org/10.22037/ijpr.2020.1101004

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