Novel Bi-heterocycles as Potent Inhibitors of Urease and Less Cytotoxic Agents: 3-({5-((2-Amino-1,3-thiazol-4-yl)methyl)-1,3,4-oxadiazol-2-yl}sulfanyl)-N-(un/substituted-phenyl)propanamides

The synthesis of a novel series of bi-heterocyclic propanamides, 7a-l, was accomplished by S-substitution of 5-[(2-amino-1,3-thiazol-4-yl)methyl]-1,3,4-oxadiazol-2-thiol (3). The synthesis was initiated from ethyl 2-(2-amino-1,3-thiazol-4-yl)acetate (1) which was converted to corresponding hydrazide...

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Detalles Bibliográficos
Autores principales: Abbasi, Muhammad Athar, Ramzan, Muhammad Shahid, ur-Rehman, Aziz, Siddiqui, Sabahat Zahra, Hassan, Mubashir, Ali Shah, Syed Adnan, Ashraf, Muhammad, Shahid, Muhammad, Seo, Sung-Yum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462494/
https://www.ncbi.nlm.nih.gov/pubmed/32922502
http://dx.doi.org/10.22037/ijpr.2019.13084.11362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462494/
https://www.ncbi.nlm.nih.gov/pubmed/32922502
http://dx.doi.org/10.22037/ijpr.2019.13084.11362

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