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NF-κB-dependent Mechanism of Action of c-Myc Inhibitor 10058-F4: Highlighting a Promising Effect of c-Myc Inhibition in Leukemia Cells, Irrespective of p53 Status

Due to the frequent contribution in the pathogenesis of different human malignancies, c-Myc is among those transcription factors that are believed to be pharmacologically targeted for cancer therapeutic approaches. In the present study, we examined the anti-leukemic effect of a well-known c-Myc inhi...

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Detalles Bibliográficos
Autores principales: Sayyadi, Mohammad, Safaroghli-Azar, Ava, Safa, Majid, Abolghasemi, Hassan, Momeny, Majid, Bashash, Davood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462502/
https://www.ncbi.nlm.nih.gov/pubmed/32922477
http://dx.doi.org/10.22037/ijpr.2020.112926.14018