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Axonal mechanisms mediating γ-aminobutyric acid receptor type A (GABA-A) inhibition of striatal dopamine release

Axons of dopaminergic neurons innervate the striatum where they contribute to movement and reinforcement learning. Past work has shown that striatal GABA tonically inhibits dopamine release, but whether GABA-A receptors directly modulate transmission or act indirectly through circuit elements is unr...

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Detalles Bibliográficos
Autores principales: Kramer, Paul F, Twedell, Emily L, Shin, Jung Hoon, Zhang, Renshu, Khaliq, Zayd M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462615/
https://www.ncbi.nlm.nih.gov/pubmed/32870779
http://dx.doi.org/10.7554/eLife.55729