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Site-selective C-H hydroxylation of pentacyclic triterpenoids directed by transient chiral pyridine-imino groups

Pentacyclic triterpenoids (PTs) constitute one of the biggest families of natural products, many with higher oxidation state at the D/E rings possess a wide spectrum of biological activties but are poorly accessible. Here we report a site-selective C-H hydroxylation at the D/E rings of PTs paving a...

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Detalles Bibliográficos
Autores principales: Mu, Tong, Wei, Bingcheng, Zhu, Dapeng, Yu, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462855/
https://www.ncbi.nlm.nih.gov/pubmed/32873790
http://dx.doi.org/10.1038/s41467-020-18138-9