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(1)H, (13)C, (15)N chemical shift assignments of SHP2 SH2 domains in complex with PD-1 immune-tyrosine motifs

Inhibition of immune checkpoint receptor Programmed Death-1 (PD-1) via monoclonal antibodies is an established anticancer immunotherapeutic approach. This treatment has been largely successful; however, its high cost demands equally effective, more affordable alternatives. To date, the development o...

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Detalles Bibliográficos
Autores principales: Marasco, Michelangelo, Kirkpatrick, John P., Carlomagno, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462904/
https://www.ncbi.nlm.nih.gov/pubmed/32236803
http://dx.doi.org/10.1007/s12104-020-09941-y