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SGLT2 and cancer

Glycolysis plays a central role in tumor metabolism and growth, and this is reflected in a high rate of glucose uptake. It is commonly assumed that the upregulation of the facilitated glucose transporter GLUT1 meets the tumor’s demand for sugar. This underlies the success in using 2FDG PET imaging i...

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Detalles Bibliográficos
Autor principal: Wright, Ernest M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462911/
https://www.ncbi.nlm.nih.gov/pubmed/32820343
http://dx.doi.org/10.1007/s00424-020-02448-4