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Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application

Sodium glucose transporters (SGLTs) belong to the mammalian solute carrier family SLC5. This family includes 12 different members in human that mediate the transport of sugars, vitamins, amino acids, or smaller organic ions such as choline. The SLC5 family belongs to the sodium symporter family (SSS...

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Detalles Bibliográficos
Autores principales: Gyimesi, Gergely, Pujol-Giménez, Jonai, Kanai, Yoshikatsu, Hediger, Matthias A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462921/
https://www.ncbi.nlm.nih.gov/pubmed/32767111
http://dx.doi.org/10.1007/s00424-020-02433-x