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CD109 mediates tumorigenicity and cancer aggressiveness via regulation of EGFR and STAT3 signalling in cervical squamous cell carcinoma

BACKGROUND: CD109 was involved in the tumorigenesis and progression of various cancers via TGF-β1 signalling and STAT3 activation. As CD109 is strongly expressed in cervical squamous cell carcinoma, this study was conducted to investigate its functional characteristics in cervical cancer. METHODS: C...

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Detalles Bibliográficos
Autores principales: Mo, Xue-Tang, Leung, Thomas Ho-Yin, Tang, Hermit Wai-Man, Siu, Michelle Kwan-Yee, Wan, Peter Kok-Ting, Chan, Karen Kar-Loen, Cheung, Annie Nga-Yin, Ngan, Hextan Yuen-Sheung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463003/
https://www.ncbi.nlm.nih.gov/pubmed/32507856
http://dx.doi.org/10.1038/s41416-020-0922-7