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Currently favored sampling practices for tumor sequencing can produce optimal results in the clinical setting
Tumor heterogeneity is a consequence of clonal evolution, resulting in a fractal-like architecture with spatially separated main clones, sub-clones and single-cells. As sequencing an entire tumor is not feasible, we ask the question whether there is an optimal clinical sampling strategy that can han...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463012/ https://www.ncbi.nlm.nih.gov/pubmed/32873813 http://dx.doi.org/10.1038/s41598-020-71382-3 |