Honeybee venom and melittin suppress growth factor receptor activation in HER2-enriched and triple-negative breast cancer

Despite decades of study, the molecular mechanisms and selectivity of the biomolecular components of honeybee (Apis mellifera) venom as anticancer agents remain largely unknown. Here, we demonstrate that honeybee venom and its major component melittin potently induce cell death, particularly in the...

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Detalles Bibliográficos
Autores principales: Duffy, Ciara, Sorolla, Anabel, Wang, Edina, Golden, Emily, Woodward, Eleanor, Davern, Kathleen, Ho, Diwei, Johnstone, Elizabeth, Pfleger, Kevin, Redfern, Andrew, Iyer, K. Swaminathan, Baer, Boris, Blancafort, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463160/
https://www.ncbi.nlm.nih.gov/pubmed/32923684
http://dx.doi.org/10.1038/s41698-020-00129-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463160/
https://www.ncbi.nlm.nih.gov/pubmed/32923684
http://dx.doi.org/10.1038/s41698-020-00129-0

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