PI3K Abrogation Using Pan-PI3K Inhibitor BKM120 Gives Rise to a Significant Anticancer Effect on AML-Derived KG-1 Cells by Inducing Apoptosis and G2/M Arrest

OBJECTIVE: The association between PI3K overexpression and the acquisition of chemoresistance has attracted tremendous attention to this axis as an appealing target to revolutionize the conventional treatment strategies of human cancers. In the present study, we aimed to survey the inhibitory impact...

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Detalles Bibliográficos
Autores principales: Sadeghi, Soroush, Esmaeili, Shadi, Pourbagheri-Sigaroodi, Atieh, Safaroghli-Azar, Ava, Bashash, Davood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463220/
https://www.ncbi.nlm.nih.gov/pubmed/32160736
http://dx.doi.org/10.4274/tjh.galenos.2020.2019.0440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463220/
https://www.ncbi.nlm.nih.gov/pubmed/32160736
http://dx.doi.org/10.4274/tjh.galenos.2020.2019.0440

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