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PI3K Abrogation Using Pan-PI3K Inhibitor BKM120 Gives Rise to a Significant Anticancer Effect on AML-Derived KG-1 Cells by Inducing Apoptosis and G2/M Arrest
OBJECTIVE: The association between PI3K overexpression and the acquisition of chemoresistance has attracted tremendous attention to this axis as an appealing target to revolutionize the conventional treatment strategies of human cancers. In the present study, we aimed to survey the inhibitory impact...
Autores principales: | Sadeghi, Soroush, Esmaeili, Shadi, Pourbagheri-Sigaroodi, Atieh, Safaroghli-Azar, Ava, Bashash, Davood |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Galenos Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463220/ https://www.ncbi.nlm.nih.gov/pubmed/32160736 http://dx.doi.org/10.4274/tjh.galenos.2020.2019.0440 |
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