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Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development

Presynaptic spike timing-dependent long-term depression (t-LTD) at hippocampal CA3-CA1 synapses is evident until the 3(rd) postnatal week in mice, disappearing during the 4(th) week. At more mature stages, we found that the protocol that induced t-LTD induced t-LTP. We characterized this form of t-L...

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Detalles Bibliográficos
Autores principales: Falcón-Moya, Rafael, Pérez-Rodríguez, Mikel, Prius-Mengual, José, Andrade-Talavera, Yuniesky, Arroyo-García, Luis E., Pérez-Artés, Rocío, Mateos-Aparicio, Pedro, Guerra-Gomes, Sónia, Oliveira, João Filipe, Flores, Gonzalo, Rodríguez-Moreno, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463247/
https://www.ncbi.nlm.nih.gov/pubmed/32873805
http://dx.doi.org/10.1038/s41467-020-18024-4