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Selective Disruption of Synaptic BMP Signaling by a Smad Mutation Adjacent to the Highly Conserved H2 Helix

Bone morphogenetic proteins (BMPs) shape normal development and function via canonical and noncanonical signaling pathways. BMPs initiate canonical signaling by binding to transmembrane receptors that phosphorylate Smad proteins and induce their translocation into the nucleus and regulation of targe...

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Detalles Bibliográficos
Autores principales: Nguyen, Tho Huu, Han, Tae Hee, Newfeld, Stuart J., Serpe, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463279/
https://www.ncbi.nlm.nih.gov/pubmed/32737119
http://dx.doi.org/10.1534/genetics.120.303484