Using serpins cysteine protease cross-specificity to possibly trap SARS-CoV-2 Mpro with reactive center loop chimera

Human serine protease inhibitors (serpins) are the main inhibitors of serine proteases, but some of them also have the capability to effectively inhibit cysteine proteases. Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) main protease (Mpro) is a chymotrypsin-type cysteine protease that...

Descripción completa

Detalles Bibliográficos
Autores principales: Jairajpuri, Mohamad Aman, Ansari, Shoyab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Host-Microbe Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463295/
https://www.ncbi.nlm.nih.gov/pubmed/32869854
http://dx.doi.org/10.1042/CS20200767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463295/
https://www.ncbi.nlm.nih.gov/pubmed/32869854
http://dx.doi.org/10.1042/CS20200767

Ejemplares similares