Genome‐wide profiling of circulating tumor DNA depicts landscape of copy number alterations in pancreatic cancer with liver metastasis

Cell‐free DNA (cfDNA) offers an alternative to tissue biopsies for genomic profiling in tumors. Here, we sought to evaluate copy number alterations in PDAC through whole‐genome sequencing (WGS) of cfDNA and determine their clinical significance. Using shallow WGS across 90 plasma samples from 70 pan...

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Detalles Bibliográficos
Autores principales: Wei, Tao, Zhang, Jian, Li, Jin, Chen, Qi, Zhi, Xiao, Tao, Wei, Ma, Jingjiao, Yang, Jiaqi, Lou, Yu, Ma, Tao, Li, Xiang, Zhang, Qi, Chen, Wei, Que, Risheng, Gao, Shunliang, Bai, Xueli, Liang, Tingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463305/
https://www.ncbi.nlm.nih.gov/pubmed/32593194
http://dx.doi.org/10.1002/1878-0261.12757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463305/
https://www.ncbi.nlm.nih.gov/pubmed/32593194
http://dx.doi.org/10.1002/1878-0261.12757

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