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Neuroendocrine subtypes of small cell lung cancer differ in terms of immune microenvironment and checkpoint molecule distribution

Small cell lung cancer (SCLC) has recently been subcategorized into neuroendocrine (NE)‐high and NE‐low subtypes showing ‘immune desert’ and ‘immune oasis’ phenotypes, respectively. Here, we aimed to characterize the tumor microenvironment according to immune checkpoints and NE subtypes in human SCL...

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Detalles Bibliográficos
Autores principales: Dora, David, Rivard, Christopher, Yu, Hui, Bunn, Paul, Suda, Kenichi, Ren, Shengxiang, Lueke Pickard, Shivaun, Laszlo, Viktoria, Harko, Tunde, Megyesfalvi, Zsolt, Moldvay, Judit, Hirsch, Fred R., Dome, Balazs, Lohinai, Zoltan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463307/
https://www.ncbi.nlm.nih.gov/pubmed/32506804
http://dx.doi.org/10.1002/1878-0261.12741